Absence of an effect of partial hepatectomy on aflatoxin B 1 carcinogenesis.
نویسندگان
چکیده
The effect of partial hepatectomy on aflatoxin B! (AFB,) carcinogenesis in rat liver has been examined in Fischer and Sprague-Dawley rats. Partial hepatectomy performed before or after the administration of AFB, had no effect on the development of hepatocarcinoma, compared to either sham hepatectomy or no operation. When AFB, administration was begun 6 hr after either hepatectomy or sham operation, the incidence of carcinoma was less than that found when AFB] treatment was begun between 24 hr and 6 days after surgery. Sprague-Dawley rats were less sensitive than Fischer rats to the carcinogenic effects of AFB!.
منابع مشابه
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عنوان ژورنال:
- Cancer research
دوره 31 5 شماره
صفحات -
تاریخ انتشار 1971